Efficient synthesis of new antiproliferative steroidal hybrids using the molecular hybridization approach-Reference-Cited by-同舟云学术

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Efficient synthesis of new antiproliferative steroidal hybrids using the molecular hybridization approach

Published:2016-07 Issue: Volume:117 Page:241-255
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Yu Bin,Qi Ping-Ping,Shi Xiao-Jing,Huang Ruilei^ORCID,Guo Hao,Zheng Yi-Chao,Yu De-Quan,Liu Hong-Min^ORCID

Funder

Natural Science Foundation of China

Development Foundation of Priority, Ministry of Education

Zhengzhou University

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference49 articles.

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2. The discovery of polo-like kinase 4 inhibitors: identification of (1R,2S)-2-(3-((E)-4-(((cis)-2,6-dimethylmorpholino)methyl)styryl)-1H-indazol-6-yl)-5′-methoxyspiro[cyclopropane-1,3′-indolin]-2′-one (CFI-400945) as a potent, orally active antitumor agent;Sampson;J. Med. Chem.,2015

3. Discovery of orally active anticancer candidate CFI-400945 derived from biologically promising spirooxindoles: success and challenges;Yu;Eur. J. Med. Chem.,2015

4. Second generation steroidal 4-Aminoquinolines are potent, dual-target inhibitors of the botulinum neurotoxin serotype a metalloprotease and P. Falciparum Malaria;Videnović;J. Med. Chem.,2014

5. Triazole–dithiocarbamate based selective lysine specific demethylase 1 (LSD1) inactivators inhibit gastric cancer cell growth, invasion, and migration;Zheng;J. Med. Chem.,2013

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