Targeting Alzheimer's disease by investigating previously unexplored chemical space surrounding the cholinesterase inhibitor donepezil
Author:
Funder
National Research Foundation (NRF) of South Africa
University of Pretoria
Publisher
Elsevier BV
Subject
Organic Chemistry,Drug Discovery,Pharmacology,General Medicine
Reference47 articles.
1. Functional network disruption in the degenerative dementias;Pievani;Lancet Neurol.,2011
2. Acetylcholinesterase inhibitors as Alzheimer therapy: from nerve toxins to neuroprotection;Singh;Eur. J. Med. Chem.,2013
3. A century of Alzheimer's disease;Goedert;Science,2006
4. Multi-target-directed drug design strategy: from a dual binding site acetylcholinesterase inhibitor to a trifunctional compound against Alzheimer's disease;Bolognesi;J. Med. Chem.,2007
5. Neuroprotective and cholinergic properties of multifunctional glutamic acid derivatives for the treatment of Alzheimer's disease;Arce;J. Med. Chem.,2009
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