Discovery, synthesis and mechanism study of 2,3,5-substituted [1,2,4]-thiadiazoles as covalent inhibitors targeting 3C-Like protease of SARS-CoV-2-Reference-Cited by-同舟云学术

Discovery, synthesis and mechanism study of 2,3,5-substituted [1,2,4]-thiadiazoles as covalent inhibitors targeting 3C-Like protease of SARS-CoV-2

Published:2023-03 Issue: Volume:249 Page:115129
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Ren Pengxuan,Yu Changyue,Zhang Ruxue,Nie Tianqing,Hu Qiaoyu,Li Hui,Zhang Xianglei,Zhang Xueyuan,Li Shiwei,Liu Lu,Dai Wenhao,Li Jian,Xu Yechun,Su Haixia,Zhang Leike,Liu Hong,Bai Fang

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

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1. Progress in Research on Inhibitors Targeting SARS-CoV-2 Main Protease (M^pro);ACS Omega;2024-08-02

2. Sustainable and practical semi-heterogeneous photosynthesis of 5-amino-1,2,4-thiadiazoles over WS2/TEMPO;Chinese Chemical Letters;2024-08

3. Non-peptidic inhibitors targeting SARS-CoV-2 main protease: A review;Bioorganic Chemistry;2024-06

4. Therapeutic cysteine protease inhibitors: a patent review (2018–present);Expert Opinion on Therapeutic Patents;2024-02

5. The expanding repertoire of covalent warheads for drug discovery;Drug Discovery Today;2023-12