Shifting the selectivity of pyrido[2,3-d]pyrimidin-7(8H)-one inhibitors towards the salt-inducible kinase (SIK) subfamily
Author:
Publisher
Elsevier BV
Subject
Organic Chemistry,Drug Discovery,Pharmacology,General Medicine
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1. Back-Pocket Optimization of 2-Aminopyrimidine-Based Macrocycles Leads to Potent EPHA2/GAK Kinase Inhibitors;Journal of Medicinal Chemistry;2024-07-19
2. The structures of salt-inducible kinase 3 in complex with inhibitors reveal determinants for binding and selectivity;Journal of Biological Chemistry;2024-05
3. Development of Selective Pyrido[2,3-d]pyrimidin-7(8H)-one-Based Mammalian STE20-Like (MST3/4) Kinase Inhibitors;Journal of Medicinal Chemistry;2024-02-29
4. Synthesis of Pyrazole-Based Macrocycles Leads to a Highly Selective Inhibitor for MST3;Journal of Medicinal Chemistry;2023-12-21
5. Development of selective pyrido[2,3-d]pyrimidin-7(8H)-one-based Mammalian STE20-like (MST3/4) kinase inhibitors;2023-11-25
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