Structure–activity relationship and properties optimization of a series of Quinazoline-2,4-diones as inhibitors of the canonical Wnt pathway

Author:

Nencini AriannaORCID,Pratelli Carmela,Quinn Joanna M.,Salerno Massimiliano,Tunici Patrizia,De Robertis Alessandra,Valensin Silvia,Mennillo Federica,Rossi Marco,Bakker AnnetteORCID,Benicchi Tiziana,Cappelli Federico,Turlizzi Elisa,Nibbio MartinaORCID,Caradonna Nicola P.,Zanelli UgoORCID,Andreini Matteo,Magnani Matteo,Varrone Maurizio

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference46 articles.

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3. Mining the Wnt pathway for cancer therapeutics;Barker;Nat. Rev. Drug Discov.,2006

4. Wnt/beta-catenin signaling: components, mechanism and disease;MacDonald;Dev. Cell,2009

5. Mechanisms of Wnt signaling in development;Wodarz;Annu. Rev. Cell Dev. Biol.,1998

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