Development of chemical probes for the bromodomains of BRD7 and BRD9
Author:
Funder
Innovative Medicines Initiative (EU/EFPIA)
Publisher
Elsevier BV
Subject
Drug Discovery,Molecular Medicine
Reference45 articles.
1. The bromodomain: a conserved sequence found in human, Drosophila and yeast proteins;Haynes;Nucleic Acids Res,1992
2. Histone recognition and large-scale structural analysis of the human bromodomain family;Filippakopoulos;Cell,2012
3. Targeting bromodomains: epigenetic readers of lysine acetylation;Filippakopoulos;Nat Rev Drug Discov,2014
4. Proteomic and bioinformatic analysis of mammalian SWI/SNF complexes identifies extensive roles in human malignancy;Kadoch;Nat Genet,2013
5. Polybromo-associated BRG1-associated factor components BRD7 and BAF180 are critical regulators of p53 required for induction of replicative senescence;Burrows;Proc Natl Acad Sci USA,2010
Cited by 13 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Epigenetic modulation by targeting bromodomain containing protein 9 (BRD9): Its therapeutic potential and selective inhibition;International Journal of Biological Macromolecules;2023-03
2. Identification of Selective BRD9 Inhibitor via Integrated Computational Approach;International Journal of Molecular Sciences;2022-11-04
3. Introducing structure-based three-dimensional pharmacophore models for accelerating the discovery of selective BRD9 binders;Bioorganic Chemistry;2022-01
4. Theoretical exploration of the binding selectivity of inhibitors to BRD7 and BRD9 with multiple short molecular dynamics simulations;RSC Advances;2022
5. Selectively targeting individual bromodomain: Drug discovery and molecular mechanisms;Pharmacological Research;2021-10
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3