Selectively targeting individual bromodomain: Drug discovery and molecular mechanisms

Author:

Wang Qianqian,Shao Xiaomin,Leung Elaine Lai Han,Chen Yingqing,Yao XiaojunORCID

Funder

National Natural Science Foundation of China

Science and Technology Development Fund

Department of Education of Liaoning Province

Dalian Science and Technology Innovation Fund

Publisher

Elsevier BV

Subject

Pharmacology

Reference138 articles.

1. Translating the histone code;Jenuwein;Science,2001

2. Histone recognition and large-scale structural analysis of the human bromodomain family;Filippakopoulos;Cell,2012

3. The bromodomain: from epigenome reader to druggable target;Sanchez;Biochim. Biophys. Acta,1839

4. The mechanisms behind the therapeutic activity of BET bromodomain inhibition;Shi;Mol. Cell,2014

5. The role of human bromodomains in chromatin biology and gene transcription;Sanchez;Curr. Opin. Drug Discov. Devel.,2009

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