Structure driven compound optimization in targeted protein degradation
Author:
Publisher
Elsevier BV
Subject
Drug Discovery,Molecular Medicine
Reference78 articles.
1. Structure-based drug design: aiming for a perfect fit;van Montfort;Essays Biochem,2017
2. A medicinal chemistry perspective on structure-based drug design and development;Maddaford,2012
3. Protein data Bank (PDB): the single global macromolecular structure archive;Burley,2017
4. Advantages of crystallographic fragment screening: functional and mechanistic insights from a powerful platform for efficient drug discovery;Patel;Prog Biophys Mol Biol,2014
5. The SGC beyond structural genomics: redefining the role of 3D structures by coupling genomic stratification with fragment-based discovery;Bradley;Essays Biochem,2017
Cited by 21 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Regulated induced proximity targeting chimeras—RIPTACs—A heterobifunctional small molecule strategy for cancer selective therapies;Cell Chemical Biology;2024-08
2. The impact of E3 ligase choice on PROTAC effectiveness in protein kinase degradation;Drug Discovery Today;2024-07
3. Synergizing Proteolysis-Targeting Chimeras and Nanoscale Exosome-Based Delivery Mechanisms for HIV and Antiviral Therapeutics;ACS Applied Nano Materials;2024-02-08
4. Pharmacophore-based ML model to filter candidate E3 ligands and predict E3 Ligase binding probabilities;Informatics in Medicine Unlocked;2024
5. Gluing the pieces together;Science;2023-11-17
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3