Regio- and stereoselective oxidation of propranolol enantiomers by human CYP2D6, cynomolgus monkey CYP2D17 and marmoset CYP2D19

Author:

Narimatsu Shizuo,Nakata Toshiyuki,Shimizudani Takeshi,Nagaoka Kenjiro,Nakura Hironori,Masuda Kazufumi,Katsu Takashi,Koeda Akiko,Naito Shinsaku,Yamano Shigeru,Miyata Atsuro,Hanioka Nobumitsu

Publisher

Elsevier BV

Subject

Toxicology,General Medicine

Reference22 articles.

1. Pharmacogenomics: translating functional genomics into rational therapeutics;Evans;Science,1999

2. The home page of Dr. David Nelson; http://drnelson.uthsc.edu/CytochromeP450.html.

3. Human cytochrome P450 enzymes: a status report summarizing their reactions, substrates, inducers and inhibitors;Rendic;Drug Metab. Rev.,1997

4. Functional pharmacogenetics/genomics of human cytochrome P450 involved in drug biotransformation;Zanger;Anal. Bioanal. Chem.,2008

5. Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians;Shimada;J. Pharmacol. Exp. Ther.,1994

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