Discovery of novel selective PI3Kγ inhibitors through combining machine learning-based virtual screening with multiple protein structures and bio-evaluation-Reference-Cited by-同舟云学术

Discovery of novel selective PI3Kγ inhibitors through combining machine learning-based virtual screening with multiple protein structures and bio-evaluation

Published:2022-02 Issue: Volume:36 Page:1-13
ISSN:2090-1232
Container-title:Journal of Advanced Research
language:en
Short-container-title:Journal of Advanced Research

Author:

Zhu Jingyu,Li Kan,Xu Lei,Cai Yanfei,Chen Yun,Zhao Xinling^ORCID,Li Huazhong,Huang Gang,Jin Jian

Funder

Fundamental Research Funds for the Central Universities

National Natural Science Foundation of China

Publisher

Elsevier BV

Subject

Multidisciplinary

Reference60 articles.

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4. Targeting the phosphatidylinositol 3-kinase/AKT pathway for the treatment of multiple myeloma;Zhu;Curr Med Chem,2014

5. Drug discovery approaches targeting the PI3K/Akt pathway in cancer;Garcia-Echeverria;Oncogene,2008

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