Receptor activation is distinct from hormone binding in intact lutropin-choriogonadotropin receptors and Asp397 is important for receptor activation.
Author:
Publisher
Elsevier BV
Subject
Cell Biology,Molecular Biology,Biochemistry
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1. Determination of different putative allosteric binding pockets at the lutropin receptor by using diverse drug-like low molecular weight ligands;Molecular and Cellular Endocrinology;2012-04
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3. The N-terminal domain of CCL21 reconstitutes high affinity binding, G protein activation, and chemotactic activity, to the C-terminal domain of CCL19;Biochemical and Biophysical Research Communications;2006-09
4. Interactions between the extracellular domain and the extracellular loops as well as the 6th transmembrane domain are necessary for TSH receptor activation;European Journal of Endocrinology;2005-04
5. Modulation of Ligand Selectivity Associated with Activation of the Transmembrane Region of the Human Follitropin Receptor;Molecular Endocrinology;2004-08-01
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