Inactivation of human placental 17 beta-estradiol dehydrogenase and 20 alpha-hydroxysteroid dehydrogenase with active site-directed 17 beta-propynyl-substituted progestin analogs.
Author:
Publisher
Elsevier BV
Subject
Cell Biology,Molecular Biology,Biochemistry
Reference15 articles.
1. Estradiol 17β-dehydrogenase and 20α-hydroxysteroid dehydrogenase from human placental cytosol: one enzyme with two activities?
2. Human placental 17 beta-estradiol dehydrogenase and 20 alpha-hydroxysteroid dehydrogenase. Two activities at a single enzyme active site.
3. Crystallization of human placental estradiol 17beta-dehydrogenase. A new method for crystallizing labile enzymes.
4. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
5. Synthesis of 17β-[(1S)-1-hydroxy-2-propynyl]- and 17β-[(1R)-1-hydroxy-2-propynyl]androst-4--en-3-one. Potential suicide substrates of 20α- and 20β- hydroxysteroid dehydrogenases
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1. 17β-Hydroxysteroid dehydrogenase inhibitors: a patent review;Expert Opinion on Therapeutic Patents;2010-07-20
2. Expression analysis of the genes involved in estradiol and progesterone action in human ovarian endometriosis;Gynecological Endocrinology;2007-01
3. Estradiol−Adenosine Hybrid Compounds Designed to Inhibit Type 1 17β-Hydroxysteroid Dehydrogenase;Journal of Medicinal Chemistry;2005-11-18
4. A concerted, rational design of type 1 17β‐hydroxysteroid dehydrogenase inhibitors: estradiol‐adenosine hybrids with high affinity;The FASEB Journal;2002-09-05
5. A 6β-(thiaheptanamide) derivative of estradiol as inhibitor of 17β-hydroxysteroid dehydrogenase type 1;The Journal of Steroid Biochemistry and Molecular Biology;1998-02
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