Synthesis of 17β-[(1S)-1-hydroxy-2-propynyl]- and 17β-[(1R)-1-hydroxy-2-propynyl]androst-4--en-3-one. Potential suicide substrates of 20α- and 20β- hydroxysteroid dehydrogenases
Author:
Publisher
Elsevier BV
Subject
Organic Chemistry,Clinical Biochemistry,Pharmacology,Endocrinology,Molecular Biology,Biochemistry
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1. 17 -Hydroxysteroid dehydrogenase: inhibitors and inhibitor design;Endocrine Related Cancer;1996-03-01
2. Mechanism Based Inhibition of Hydroxysteroid Dehydrogenases;Journal of Enzyme Inhibition;1991-01
3. Active-site directed inactivation of rat ovarian 20 α-hydroxysteroid dehydrogenase;Biochemical Journal;1986-12-15
4. Synthesis and characteristics of allylic 4-pregnene-3,20-diols found in gonadal and breast tissues;Steroids;1986-04
5. Inactivation of human placental 17 beta,20 alpha-hydroxysteroid dehydrogenase by 16-methylene estrone, an affinity alkylator enzymatically generated from 16-methylene estradiol-17 beta.;Journal of Biological Chemistry;1983-10
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