A case study on quantitative in vitro to in vivo extrapolation for environmental esters: Methyl-, propyl- and butylparaben

Author:

Campbell Jerry L.,Yoon Miyoung,Clewell Harvey J.

Publisher

Elsevier BV

Subject

Toxicology

Reference33 articles.

1. Metabolism of parabens (4-hydroxybenzoic acid esters) by hepatic esterases and UDP- glucuronosyltransferases in man;Abbas;Drug Metab. Pharmacokinet.,2010

2. Final amended report on the safety assessment of methylparaben, ethylparaben, propylparaben, isopropylparaben, butylparaben, isobutylparaben, and benzylparaben as used in cosmetic products;Andersen;Int. J. Toxicol.,2008

3. HPLC determination of pKa of parabens and investigation on their lipophilicity parameters;Angelov;J. Liq. Chromatogr. Relat. Technol.,2008

4. Systemic exposure to parabens: pharmacokinetics, tissue distribution, excretion balance and plasma metabolites of [14C]-methyl-, propyl- and butylparaben in rats after oral, topical or subcutaneous administration;Aubert;Food Chem Toxicol.,2012

5. Physiological parameter values for physiologically based pharmacokinetic models;Brown;Toxicol. Ind. Health,1997

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