Protein and Nucleotide Biosynthesis Are Coupled by a Single Rate-Limiting Enzyme, PRPS2, to Drive Cancer
Author:
Publisher
Elsevier BV
Subject
General Biochemistry, Genetics and Molecular Biology
Reference56 articles.
1. The c-myc oncogene driven by immunoglobulin enhancers induces lymphoid malignancy in transgenic mice;Adams;Nature,1985
2. Suppression of nucleotide metabolism underlies the establishment and maintenance of oncogene-induced senescence;Aird;Cell Rep.,2013
3. Suppression of Myc oncogenic activity by ribosomal protein haploinsufficiency;Barna;Nature,2008
4. Cloning of cDNAs for human phosphoribosylpyrophosphate synthetases 1 and 2 and X chromosome localization of PRPS1 and PRPS2 genes;Becker;Genomics,1990
5. Stimulation of de novo pyrimidine synthesis by growth signaling through mTOR and S6K1;Ben-Sahra;Science,2013
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