Standardized whole blood stimulation improves immunomonitoring of induced immune responses in multi-center study

Author:

Duffy DarraghORCID,Rouilly Vincent,Braudeau Cecile,Corbière Véronique,Djebali Raouf,Ungeheuer Marie-Noelle,Josien RegisORCID,LaBrie Samuel T.,Lantz Olivier,Louis Delphine,Martinez-Caceres Eva,Mascart Francoise,Ruiz de Morales Jose G.,Ottone Catherine,Redjah Lydia,Guen Nina Salabert-Le,Savenay Alain,Schmolz Manfred,Toubert Antoine,Albert Matthew L.

Funder

Milieu Interieur Consortium

Publisher

Elsevier BV

Subject

Immunology,Immunology and Allergy

Reference22 articles.

1. Isolation and preservation of peripheral blood mononuclear cells for analysis of islet antigen-reactive T cell responses: position statement of the T-Cell Workshop Committee of the Immunology of Diabetes Society;Mallone;Clin. Exp. Immunol.,2011

2. Functional analysis via standardized whole-blood stimulation systems defines the boundaries of a healthy immune response to complex stimuli;Duffy;Immunity,2014

3. Optimization of a whole blood intracellular cytokine assay for measuring innate cell responses to mycobacteria;Shey;J. Immunol. Methods,2012

4. Synthesis of tumor necrosis factor alpha and interleukin-1 receptor antagonist, but not interleukin-1, by human mononuclear cells is enhanced by exposure of whole blood to shear stress;Pomianek;ASAIO J. Am. Soc. Artif. Intern. Organs,1996

5. Neutrophils in the activation and regulation of innate and adaptive immunity;Mantovani;Nat. Rev. Immunol.,2011

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