Interferon-β therapy downregulates the anti-apoptosis protein FLIP in T cells from patients with multiple sclerosis

Author:

Sharief M.K,Semra Y.K,Seidi O.A,Zoukos Y

Publisher

Elsevier BV

Subject

Neurology (clinical),Neurology,Immunology,Immunology and Allergy

Reference55 articles.

1. Cell cycle-dependent regulation of FLIP levels and susceptibility to Fas-mediated apoptosis;Algeciras;J. Immunol.,1999

2. Multiple sclerosis—emerging concepts of disease pathogenesis;Antel;J. Neuroimmunol.,1999

3. Activation of the dsRNA-dependent protein kinase, PKR, induces apoptosis through FADD-mediated death signaling;Balachandran;EMBO J.,1998

4. Alpha/beta interferons potentiate virus-induced apoptosis through activation of the FADD/Caspase-8 death signaling pathway;Balachandran;J. Virol.,2000

5. Molecular pathogenesis of multiple sclerosis;Bar-Or;J. Neuroimmunol.,1999

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