Case Examples of Using Quantitative Pharmacology in Developing Therapeutic Proteins in Multiple Sclerosis - Peginterferon Beta-1a, Daclizumab Beta, Natalizumab

Author:

Hu Xiao12,Hang Yaming13,Diao Lei14,Muralidharan Kumar K.1,Nestorov Ivan1

Affiliation:

1. Biogen; 225 Binney Street Cambridge MA 02142 USA

2. Wave Life Sciences; 733 Concord Ave Cambridge MA 02138 USA

3. Takeda Pharmaceuticals International Co.; Cambridge MA 02138 USA

4. BMS China; 15F, Wheelock Square, 1717 West Nanjing Road Shanghai China

Publisher

John Wiley & Sons, Inc.

Reference71 articles.

1. Sex ratio of multiple sclerosis in Canada: a longitudinal study;Orton;Lancet Neurol.,2006

2. Disability in multiple sclerosis: a reference for patients and clinicians;Kister;Neurology,2013

3. Incidence and prevalence of multiple sclerosis in Olmsted County, Minnesota, 1985-2000;Mayr;Neurology,2003

4. Hersh , C.M. Fox , R.J. 2015 Multiple sclerosis http://www.clevelandclinicmeded.com/medicalpubs/diseasemanagement/neurology/multiple_sclerosis/

5. European Medicines Agency 2015 Guideline on clinical investigation of medicinal products for the treatment of multiple sclerosis http://www.thehumanmotioninstitute.org/sites/default/files/WC500185161.pdf

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