Elimination of blood-derived macrophages inhibits the release of interleukin-1 and the entry of leukocytes into the cerebrospinal fluid in experimental pneumococcal meningitis

Author:

Zysk Gregor,Brück Wolfgang,Huitinga Ingeborg,Fischer Falko R,Flachsbarth Franziska,van Rooijen Nico,Nau Roland

Publisher

Elsevier BV

Subject

Clinical Neurology,Neurology,Immunology,Immunology and Allergy

Reference29 articles.

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2. Cavaillon, J.M. (1994) Cytokines and macrophages. Biomed. Pharmacother. 48, 445–453.

3. Dacey, R.G. and Sande, M.A. (1974) Effect of probenecid on cerebrospinal fluid concentrations of penicillin and cephalosporin derivatives. Antimicrob. Agents Chemother. 6, 437–441.

4. De Rijk, R.H., Strijbos, P.J.L.M., van Rooijen, N., Rothwell, N.J. and Berkenbosch, F. (1993) Fever and thermogenesis in response to bacterial endotoxin involve macrophage-dependent mechanisms in rats. Am. J. Physiol. 265, R1179–1183.

5. De Rijk, R.H., van Rooijen, N., Tilders, F.J.H., Besedovsky, H.O., Del Rey, A. and Berkenbosch, F. (1991) Selective depletion of macrophages prevents pituitary-adrenal activation in response to subpyrogenic, but not to pyrogenic, doses of bacterial endotoxin in rats. Endocrinology 128, 330–338.

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