Characterization and effects of methyl-2- (4-aminophenyl)-1,2-dihydro-1-oxo-7- (2-pyridinylmethoxy)-4-(3,4,5-trimethoxyphenyl)-3-isoquinoline carboxylate sulfate (T-1032), a novel potent inhibitor of cGMP-binding cGMP-specific phosphodiesterase (PDE5)

Author:

Kotera Jun,Fujishige Kotomi,Michibata Hideo,Yuasa Keizo,Kubo Akira,Nakamura Yoshinori,Omori Kenji

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

Reference46 articles.

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3. Phosphodiesterase inhibitors induce endothelium-dependent relaxation of rat and rabbit aorta by potentiating the effects of spontaneously released endothelium-derived relaxing factor;Martin;J Pharmacol Exp Ther,1986

4. Endogenous nitric oxide release required for long-term synaptic depression in the cerebellum;Shibuki;Nature,1991

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