Pulmonary CYP1A1 and CYP1A2 levels and activities in adult male and female offspring of rats exposed during gestation and lactation to 2,3,7,8-tetrachlorodibenzo-p-dioxin11Abbreviations: AhR, aryl hydrocarbon receptor; ARNT, AhR nuclear translocator; AUC, area under the curve; B[a]P, benzo[a]pyrene; CYP1A, used to include CYP1A1 and CYP1A2; EROD, ethoxyresorufin O-deethylase; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; MeIQ, 2-amino-3,4-dimethylimidazo[4,5-f]quinoline; PCR, polymerase chain reaction; PhIP, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine; and TCDD, 2,3,7,8-tetrachlorodibenzo-p-dioxin.

Author:

Iba Michael M.,Fung Jacqueline

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

Reference62 articles.

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