Up-regulation of a thermogenesis-related gene (UCP1) and down-regulation of PPARγ and aP2 genes in adipose tissue: possible features of the antiobesity effects of a β3-adrenergic agonist 1 1Abbreviations: AP2, adipocyte specific fatty acid binding protein; BAT, brown adipose tissue; DIO, diet-induced obesity; HFD, high-fat diet; PPARγ, peroxisome proliferator-activated receptor gamma; RXRα, retinoid X receptor alpha; RARα, retinoid acid receptor alpha; UCP, uncoupling protein; WAT, white adipose tissue; RT-PCR, reverse transcription-polymerase chain reaction; M-MLV, Moloney-Murine Leukemia Virus.

Author:

Margareto Javier,Larrarte Eider,Marti Amelia,Martinez J.Alfredo

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

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