In vitro evaluation of reactive nature of E- and Z-guggulsterones and their metabolites in human liver microsomes using UHPLC-Orbitrap mass spectrometer

Author:

Balhara Ankit,Ladumor Mayur,Singh Dilip Kumar,Praneetha Pammi,Preethi Jalvadi,Pokharkar Sunil,Deshpande Abhijeet Yashwantrao,Giri Sanjeev,Singh Saranjit

Publisher

Elsevier BV

Subject

Clinical Biochemistry,Spectroscopy,Drug Discovery,Pharmaceutical Science,Analytical Chemistry

Reference25 articles.

1. Gugulipid;Arya;Drugs Fut.,1988

2. Gum guggul (Commiphora mukul)- the success story of an ancient insight leading to a modern discovery;Satyavati;Indian J. Med. Res.,1988

3. Guggul for hyperlipidemia : a review by the natural standard research collaboration;Ulbricht;Complement Ther. Med.,2005

4. Therapeutic effects of guggul and its constituent guggulsterone: cardiovascular benefits;Deng;Cardiovasc. Drug Rev.,2007

5. A natural product that lowers cholesterol as an antagonist ligand for FXR;Urizar;Science (80),2002

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