Characterization of the isomeric configuration and impurities of (Z)-endoxifen by 2D NMR, high resolution LC⬜MS, and quantitative HPLC analysis-Reference-Cited by-同舟云学术

Characterization of the isomeric configuration and impurities of (Z)-endoxifen by 2D NMR, high resolution LC⬜MS, and quantitative HPLC analysis

Published:2014-01 Issue: Volume:88 Page:174-179
ISSN:0731-7085
Container-title:Journal of Pharmaceutical and Biomedical Analysis
language:en
Short-container-title:Journal of Pharmaceutical and Biomedical Analysis

Author:

Elkins Phyllis,Coleman Donna,Burgess Jason,Gardner Michael,Hines John,Scott Brendan,Kroenke Michelle,Larson Jami,Lightner Melissa,Turner Gregory,White Jonathan,Liu Paul

Funder

Pharmaceutical Research Branch, DTP, DCTD, NCI, NIH, DHHS

Publisher

Elsevier BV

Subject

Clinical Biochemistry,Spectroscopy,Drug Discovery,Pharmaceutical Science,Analytical Chemistry

Reference18 articles.

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3. Endoxifen (4-hydroxy-N-desmethyl-tamoxifen) has anti-estrogenic effects in breast cancer cells with potency similar to 4-hydroxy-tamoxifen;Lim;Cancer Chemotherapy and Pharmacology,2005

4. Orally administered Endoxifen is a new therapeutic agent for breast cancer;Ahmad;Breast Cancer Research and Treatment,2010

5. Pharmacogenetics of tamoxifen biotransformation is associated with clinical outcomes of efficacy and hot flashes;Goetz;Journal of Clinical Oncology,2005

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