A validated UPLC-MS/MS method to determine free and total irinotecan and its two metabolites in human plasma after intravenous administration of irinotecan hydrochloride liposome injection-Reference-Cited by-同舟云学术

A validated UPLC-MS/MS method to determine free and total irinotecan and its two metabolites in human plasma after intravenous administration of irinotecan hydrochloride liposome injection

Published:2019-06 Issue: Volume:170 Page:112-123
ISSN:0731-7085
Container-title:Journal of Pharmaceutical and Biomedical Analysis
language:en
Short-container-title:Journal of Pharmaceutical and Biomedical Analysis

Author:

Zhuang Quankun,Liu Xuemei,Sun Zhuo,Wang Hongyun,Jiang Ji

Funder

“13th Five-Year” National Major New Drug Projects

CAMS Innovation Fund for Medical Sciences

Sichuan Kelun Pharmaceutical Research Institute Co., Ltd.

Publisher

Elsevier BV

Subject

Clinical Biochemistry,Spectroscopy,Drug Discovery,Pharmaceutical Science,Analytical Chemistry

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3. Intracellular carboxyl esterase activity is a determinant of cellular sensitivity to the antineoplastic agent KW-2189 in cell lines resistant to cisplatin and CPT-11;Ogasawara;Jpn. J. Cancer Res.: Gann.,1995

4. UGT1A1*28 polymorphism as a determinant of irinotecan disposition and toxicity;Iyer;Pharmacogenomics,2002

5. Clinical pharmacokinetics of irinotecan;Chabot;Clin. Pharmacokinet.,1997

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