Characterization of TPN729 metabolites in humans using ultra-performance liquid chromatography/quadrupole time-of-flight mass spectrometry
Author:
Publisher
Elsevier BV
Subject
Clinical Biochemistry,Spectroscopy,Drug Discovery,Pharmaceutical Science,Analytical Chemistry
Reference18 articles.
1. The selectivity and potency of the new PDE5 inhibitor TPN729MA;Wang;J. Sex. Med.,2013
2. Preclinical pharmacokinetics of TPN 729MA, a novel PDE5 inhibitor, and prediction of human pharmacokinetics using physiologically based pharmacokinetic model;Gao;Acta Pharmacol. Sin.,2015
3. Phosphodiesterase type 5 (PDE5) inhibitors in erectile dysfunction: the proper drug for the proper patient;Corona;J. Sex. Med.,2011
4. Are phosphodiesterase type 5 inhibitors associated with vision-threatening adverse events? A critical analysis and review of the literature;Azzouni;J. Sex. Med.,2011
5. Potency, selectivity, and consequences of nonselectivity of PDE inhibition;Bischoff;Int. J. Impot. Res.,2004
Cited by 12 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. An overview of conventional and investigational phosphodiesterase 5 inhibitors for treating erectile dysfunction and other conditions;Expert Opinion on Investigational Drugs;2024-08-11
2. Absorption, distribution, metabolism, and excretion of [14C]TPN729 after oral administration to rats;Xenobiotica;2022-01-02
3. Metabolite Identification in the Preclinical and Clinical Phase of Drug Development;Current Drug Metabolism;2021-09
4. Species differences in the CYP3A-catalyzed metabolism of TPN729, a novel PDE5 inhibitor;Acta Pharmacologica Sinica;2020-06-24
5. Metabolism by Aldehyde Oxidase: Drug Design and Complementary Approaches to Challenges in Drug Discovery;Journal of Medicinal Chemistry;2019-08-06
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3