Preclinical pharmacokinetics of TPN729MA, a novel PDE5 inhibitor, and prediction of its human pharmacokinetics using a PBPK model-Reference-Cited by-同舟云学术

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Preclinical pharmacokinetics of TPN729MA, a novel PDE5 inhibitor, and prediction of its human pharmacokinetics using a PBPK model

Published:2015-11-23 Issue:12 Volume:36 Page:1528-1536
ISSN:1671-4083
Container-title:Acta Pharmacologica Sinica
language:en
Short-container-title:Acta Pharmacol Sin

Author:

Gao Zhi-wei,Zhu Yun-ting,Yu Ming-ming,Zan Bin,Liu Jia,Zhang Yi-fan,Chen Xiao-yan,Li Xue-ning,Zhong Da-fang

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Pharmacology,General Medicine

Link

http://www.nature.com/articles/aps2015118.pdf

Reference34 articles.

1. Hong K, Xu QQ, Zhao YP, Gu YQ, Jiang H, Wang XF, et al. Andrology in China: current status and 10 years' progress. Asian J Androl 2011; 13: 512–8.

2. Zhang K, Xu B, Liu D, Wang X, Zhu J, Deng C, et al. Sildenafil improves erectile hardness in Chinese men with erectile dysfunction: a real-life study analyzed on age stratification. Urology 2014; 83: 831–6.

3. Gupta M, Kovar A, Meibohm B . The clinical pharmacokinetics of phosphodiesterase-5 inhibitors for erectile dysfunction. J Clin Pharmacol 2005; 45: 987–1003.

4. Francis SH, Corbin JD . Molecular mechanisms and pharmacokinetics of phosphodiesterase-5 antagonists. Curr Urol Rep 2003; 4: 457–65.

5. Corbin JD, Francis SH . Pharmacology of phosphodiesterase-5 inhibitors. Int J Clin Pract 2002; 56: 453–9.

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