A validated HPLC assay for the determination of R-(−)-gossypol in human plasma and its application in clinical pharmacokinetic studies-Reference-Cited by-同舟云学术

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A validated HPLC assay for the determination of R-(−)-gossypol in human plasma and its application in clinical pharmacokinetic studies

Published:2012-07 Issue: Volume:66 Page:371-375
ISSN:0731-7085
Container-title:Journal of Pharmaceutical and Biomedical Analysis
language:en
Short-container-title:Journal of Pharmaceutical and Biomedical Analysis

Author:

Lin Hongxia,Gounder Murugesan K.,Bertino Joseph R.,Kong Ah-Ng Tony,DiPaola Robert S.,Stein Mark N.

Publisher

Elsevier BV

Subject

Clinical Biochemistry,Spectroscopy,Drug Discovery,Pharmaceutical Science,Analytical Chemistry

Reference23 articles.

1. Clinical trial of gossypol as a male contraceptive drug. Part I. Efficacy study;Liu;Fertil. Steril.,1987

2. Gossypol blood levels and inhibition of spermatogenesis in men taking gossypol as a contraceptive. A multicenter, international, dose-finding study;Coutinho;Contraception,2000

3. AT-101 (R-(−)-gossypol acetic acid) enhances the effectiveness of androgen deprivation therapy in the VCaP prostate cancer model;McGregor;J. Cell. Biochem.,2010

4. Gossypol induces apoptosis by activating p53 in prostate cancer cells and prostate tumor-initiating cells;Volate;Mol. Cancer Ther.,2010

5. Induction of apoptosis by (−)-gossypol-enriched cottonseed oil in human breast cancer cells;Ye;Int. J. Mol. Med.,2010

Cited by 8 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Curse or Cure? A Perspective on the Developability of Aldehydes as Active Pharmaceutical Ingredients;Journal of Medicinal Chemistry;2020-09-11

2. A phase I study of AT-101, a BH3 mimetic, in combination with paclitaxel and carboplatin in solid tumors;Investigational New Drugs;2019-08-06

3. Secretome Analysis and Bioprospecting of Lignocellulolytic Fungal Consortium for Valorization of Waste Cottonseed Cake by Hydrolase Production and Simultaneous Gossypol Degradation;Waste and Biomass Valorization;2019-02-27

4. Validated method to determine (±)-gossypol inCandida tropicalisculture by high-performance liquid chromatography;Acta Chromatographica;2018-12

5. Development of an RP-UHPLC-PDA method for quantification of free gossypol in cottonseed cake and fungal-treated cottonseed cake;PLOS ONE;2018-05-23

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