Application of an LC–MS/MS method for the simultaneous quantification of human intestinal transporter proteins absolute abundance using a QconCAT technique
Author:
Funder
The Royal Commission for Exhibition of 1851
Publisher
Elsevier BV
Subject
Clinical Biochemistry,Spectroscopy,Drug Discovery,Pharmaceutical Science,Analytical Chemistry
Reference19 articles.
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3. Mechanistic pharmacokinetic modeling for the prediction of transporter-mediated disposition in humans from sandwich culture human hepatocyte data;Jones;Drug Metab. Dispos.,2012
4. Application of permeability-limited physiologically-based pharmacokinetic models: Part I—Digoxin pharmacokinetics incorporating P-glycoprotein-mediated efflux;Neuhoff;J. Pharm. Sci.,2013
5. Absolute abundance and function of intestinal drug transporters: a prerequisite for fully mechanistic in vitro–in vivo extrapolation of oral drug absorption;Harwood;Biopharm. Drug Dispos.,2013
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