Steviol, an aglycone of steviol glycoside sweeteners, interacts with the pregnane X (PXR) and aryl hydrocarbon (AHR) receptors in detoxification regulation

Author:

Dusek Jan,Carazo Alejandro,Trejtnar Frantisek,Hyrsova Lucie,Holas Ondřej,Smutny Tomas,Micuda Stanislav,Pavek PetrORCID

Funder

GACR

GAUK

SVV

Publisher

Elsevier BV

Subject

Toxicology,General Medicine,Food Science

Reference40 articles.

1. Commission regulation (EU) no 1131/2011 amending annex II to regulation (EC) no 1333/2008 of the European parliament and of the council with regard to steviol glycosides;Authority;Official J. Eur. Union,2011

2. Evaluation of a new molecular entity as a victim of metabolic drug-drug interactions-an industry perspective;Bohnert;Drug Metab. Dispos.,2016

3. Acetylated deoxycholic (DCA) and cholic (CA) acids are potent ligands of pregnane X (PXR) receptor;Carazo;Toxicol. Lett.,2017

4. Chrysin, baicalein and galangin are indirect activators of the human constitutive androstane receptor (CAR);Carazo Fernandez;Toxicol. Lett.,2015

5. Hepatocyte cell lines: their use, scope and limitations in drug metabolism studies;Castell;Expert Opin. Drug Metabolism Toxicol.,2006

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