Theoretical assessment of the performances of commercial oximes on the reactivation of acetylcholinesterase inhibited by the nerve agent A-242 (novichok)

Author:

Santos Marcelo C.,Botelho Fernanda D.,Gonçalves Arlan S.ORCID,Kuca KamilORCID,Nepovimova Eugenie,Cavalcante Samir F.A.ORCID,Lima Antonio L.S.,França Tanos C.C.ORCID

Funder

University of Hradec Kralove

Conselho Nacional de Desenvolvimento Científico e Tecnológico

Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro

Fundação de Amparo à Pesquisa e Inovação do Espírito Santo

Institute for Fiber Engineering, Shinshu University

Publisher

Elsevier BV

Subject

Toxicology,General Medicine,Food Science

Reference50 articles.

1. Acetylcholinesterase. IX. Structural features determining the inhibition by amino acids and related compounds;Bergmann;J. Biol. Chem.,1950

2. The protein data bank;Berman;Acta Crystallogr. Sect. D Biol. Crystallogr.,2002

3. Structural insights of stereospecific inhibition of human acetylcholinesterase by VX and subsequent reactivation by HI-6;Bester;Chem. Res. Toxicol.,2018

4. Theoretical study of the molecular aspect of the suspected novichok agent A234 of the Skripal poisoning;Bhakhoa;R. Soc. Open Sci.,2019

5. Recent research on Novichok;Bolt;Arch. Toxicol.,2022

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