Harnessing in vivo siRNA delivery for drug discovery and therapeutic development

Author:

Xie Frank Y.,Woodle Martin C.,Lu Patrick Y.

Publisher

Elsevier BV

Subject

Drug Discovery,Pharmacology

Reference59 articles.

1. Killing the messenger: short RNAs that silence gene expression;Dykxhoorn;Nat. Rev. Mol. Cell Biol.,2003

2. siRNA-mediated antitumorgenesis for drug target validation and therapeutics;Lu;Curr. Opin. Mol. Ther.,2003

3. RNA interference and the use of small interfering RNA to study gene function in mammalian systems;Bantounas;J. Mol. Endocrinol.,2004

4. Delivering siRNA to animal disease models for validation of novel drug targets in vivo.;Xie;PharmaGenomics,2004

5. Inhibition of ocular angiogenesis by siRNA targeting vascular endothelial growth factor pathway genes: therapeutic strategy for herpetic stromal keratitis;Kim;Am. J. Pathol.,2004

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