Introduction of germline residues improves the stability of anti-HIV mAb 2G12-IgM-Reference-Cited by-同舟云学术

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Introduction of germline residues improves the stability of anti-HIV mAb 2G12-IgM

Published:2015-10 Issue:10 Volume:1854 Page:1536-1544
ISSN:1570-9639
Container-title:Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics
language:en
Short-container-title:Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics

Author:

Chromikova Veronika,Mader Alexander,Hofbauer Stefan,Göbl Christoph,Madl Tobias^ORCID,Gach Johannes S.,Bauernfried Stefan,Furtmüller Paul G.,Forthal Donald N.,Mach Lukas,Obinger Christian,Kunert Renate^ORCID

Funder

Austrian Science Fund

Bavarian Ministry of Sciences, Research and the Arts

Austrian Academy of Sciences

German Research Foundation

Publisher

Elsevier BV

Subject

Molecular Biology,Biochemistry,Biophysics,Analytical Chemistry

Reference45 articles.

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3. Natural human immunoglobulins in cancer immunotherapy;Vollmers;Immunotherapy,2009

4. Phase I pilot clinical trial of human IgM monoclonal antibody to ganglioside GM3 in patients with metastatic melanoma;Irie;Cancer Immunol. Immunother.,2004

5. The natural human IgM antibody PAT-SM6 induces apoptosis in primary human multiple myeloma cells by targeting heat shock protein GRP78;Rasche;PLoS One,2013

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1. Interaction Studies of Hexameric and Pentameric IgMs with Serum-Derived C1q and Recombinant C1q Mimetics;Life;2024-05-17

2. Biophysical Characterization of the Oligomeric States of Recombinant Immunoglobulins Type-M and Their C1q-Binding Kinetics by Biolayer Interferometry;Frontiers in Bioengineering and Biotechnology;2022-05-24

3. Biophysical characterization of the oligomeric states of recombinant Immunoglobulins type-M and their C1q binding kinetics by Biolayer Interferometry;2021-10-01

4. Germinality does not necessarily define mAb expression and thermal stability;Applied Microbiology and Biotechnology;2019-07-26

5. Lessons learned from merging wet lab experiments with molecular simulation to improve mAb humanization;Protein Engineering, Design and Selection;2018-05-11

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