Total synthesis of Δ 12 -PGJ 2 , 15-deoxy-Δ 12,14 -PGJ 2 , and related compounds
Author:
Publisher
Elsevier BV
Subject
Organic Chemistry,Drug Discovery,Biochemistry
Reference30 articles.
1. Albumin-catalyzed metabolism of prostaglandin D2. Identification of products formed in vitro.
2. Occurrence of 9-deoxy-delta 9,delta 12-13,14-dihydroprostaglandin D2 in human urine.
3. Induction of Heme Oxygenase-1 Expression in Murine Macrophages Is Essential for the Anti-inflammatory Effect of Low Dose 15-Deoxy-Δ12,14-prostaglandin J2
4. The cyclopentenone 15-deoxy- 12,14-prostaglandin J2 binds to and activates H-Ras
5. The effects of Δ12-PGJ2 on malignant cells☆
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1. A facile synthesis of (±)-15-deoxy-Δ12,14-prostaglandin J2 methyl ester;Mendeleev Communications;2023-07
2. Development of a new approach for the synthesis of (+)-15-deoxy-Δ12,14-prostaglandin J2 methyl ester based on the [2+2]-cycloadduct of 5-trimethylsilylcyclopentadiene and dichloroketene;New Journal of Chemistry;2022
3. Applications of Transition‐Metal‐Catalyzed Asymmetric Allylic Substitution in Total Synthesis of Natural Products: An Update;The Chemical Record;2020-11-18
4. The formal synthesis of (+)-15-deoxy-Δ12,14-prostaglandin J2 by utilizing SmI2-promoted intramolecular coupling of bromoalkynes and α,β-unsaturated esters;Tetrahedron;2020-05
5. Enantioselective Synthesis of 15-Deoxy-Δ12,14-Prostaglandin J2;Organic Letters;2019-12-06
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