Synthesis of a hairpin pyrrole–imidazole polyamide conjugate containing a quinone methide precursor and vinyl linking group
Author:
Publisher
Elsevier BV
Subject
Organic Chemistry,Drug Discovery,Biochemistry
Reference24 articles.
1. DNA Cross-Linking Agents as Antitumor Drugs
2. The Purine 2-Amino Group as the Critical Recognition Element for Sequence-Specific Alkylation and Cross-Linking of DNA by Mitomycin C
3. Analysis of the monoalkylation and cross-linking sequence specificity of bizelesin, a bifunctional alkylation agent related to (+)-CC-1065
4. Mechanisms of DNA sequence selective alkylation of guanine-N7 positions by nitrogen mustards
5. Covalent structure of a nitrogen mustard-induced DNA interstrand cross-link: an N7-to-N7 linkage of deoxyguanosine residues at the duplex sequence 5'-d(GNC)
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1. The unexplored potential of quinone methides in chemical biology;Bioorganic & Medicinal Chemistry;2019-06
2. Mannich base-connected syntheses mediated by ortho-quinone methides;Beilstein Journal of Organic Chemistry;2018-03-06
3. Selective deprotection of silyl ethers;Tetrahedron;2013-03
4. Advances in DNA-Ligands with Groove Binding, Intercalating and/or Alkylating Activity: Chemistry, DNA-Binding and Biology;Current Medicinal Chemistry;2005-11-01
5. Conjugation of a Hairpin Pyrrole-Imidazole Polyamide to a Quinone Methide for Control of DNA Cross-Linking;Bioconjugate Chemistry;2004-06-04
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