The Purine 2-Amino Group as the Critical Recognition Element for Sequence-Specific Alkylation and Cross-Linking of DNA by Mitomycin C-Reference-Cited by-同舟云学术

The Purine 2-Amino Group as the Critical Recognition Element for Sequence-Specific Alkylation and Cross-Linking of DNA by Mitomycin C

Published:1998-10-28 Issue:45 Volume:120 Page:11581-11593
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Tomasz Maria¹,Das Arunangshu¹,Tang Kit S.¹,Ford Marjin G. J.¹,Minnock Andrew¹,Musser Steven M.¹,Waring Michael J.¹

Affiliation:

1. Contribution from the Department of Chemistry, Hunter College, City University of New York, New York, New York 10021, U.S. Food and Drug Administration, Washington, D.C. 20204, and Department of Pharmacology, University of Cambridge, Tennis Court Road, Cambridge CB2 1QJ, UK

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/ja9824019

Reference35 articles.

1. The 2-amino group of guanine is absolutely required for specific binding of the anti-cancer antibiotic echinomycin to DNA

2. The purine 2-amino group as a critical recognition element for binding of small molecules to DNA

3. Comparative NMR analysis of the decadeoxynucleotide d-(GCATTAATGC)2and an anlogue containing 2-aminoadenine

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