A multicomponent synthesis of gem-(β-dicarbonyl)arylmethanes

Author:

Appendino Giovanni,Cicione Lavinia,Minassi Alberto

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Reference10 articles.

1. STUDIES ON THE HEMORRHAGIC SWEET CLOVER DISEASE

2. Cancer chemotherapy with indole-3-carbinol, bis(3′-indolyl)methane and synthetic analogs

3. Identification of Indole Derivatives as Self-Growth Inhibitors of Symbiobacterium thermophilum , a Unique Bacterium Whose Growth Depends on Coculture with a Bacillus sp

4. Dicoumarol was synthesized by Hanschutz as early as in 1909 (Hanschutz, R. Liebigs Ann. Chem. 1909, 367, 169–218).

5. Some β-dicarbonyl-heteroaryl cross dimers have been prepared in a two-step protocol from the condensation of heteroaryl aldehydes and β-dicarbonyls, followed by hydrogenation of the resulting Knoevenagel adducts with Pd/CaCO3 (Velezheva, V. S.; Erofeev, Y. V.; Suvorov, N. N. Zh. Org. Khim. 1973, 9, 185–9).

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