Organo-catalyzed Michael addition of 2-fluoro-2-arylacetonitriles

Author:

Chen De-Yin,Song Shuai,Chen Ling-Yan,Ren Xinfeng,Li YaORCID

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Reference43 articles.

1. For selected reviews, see: (a) J.P. Bégué, D. Bonnet-Delpon, Bioorganic and Medicinal Chemistry of Fluorine, John Wiley & Sons: New Jersey, 2008; (b) S. Purser, P.R. Moore, S. Swallow, V. Gouverneur, Chem. Soc. Rev. 37 (2008) 320–330;(c) P.A. Champagne, J. Desroches, J.-D. Hamel, M. Vandamme, J.-F. Paquin, Chem. Rev. 115 (2015) 9073–9174; (d) H.-J. Bohm, D. Banner, S. Bendels, M. Kansy, B. Kuhn, K. Muller, U. Obst-Sander, M. Stahl, ChemBioChem 5 (2004) 637–643.

2. Asymmetric Fluorocyclizations of Alkenes

3. Advances in Catalytic Enantioselective Fluorination, Mono-, Di-, and Trifluoromethylation, and Trifluoromethylthiolation Reactions

4. Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II–III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas

5. Asymmetric Construction of Stereogenic Carbon Centers Featuring a Trifluoromethyl Group from Prochiral Trifluoromethylated Substrates

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