Synthesis of α-hydroxyalkyl dehydroazepanes via catalytic enantioselective borylative migration of an enol nonaflate-Reference-Cited by-同舟云学术

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Synthesis of α-hydroxyalkyl dehydroazepanes via catalytic enantioselective borylative migration of an enol nonaflate

Published:2018-12 Issue:49 Volume:59 Page:4334-4339
ISSN:0040-4039
Container-title:Tetrahedron Letters
language:en
Short-container-title:Tetrahedron Letters

Author:

Clement Helen A.,Hall Dennis G.

Funder

National Science and Engineering Research Council

University of Alberta

NSERC

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Reference36 articles.

1. Analysis of the Structural Diversity, Substitution Patterns, and Frequency of Nitrogen Heterocycles among U.S. FDA Approved Pharmaceuticals

2. Combining Molecular Scaffolds from FDA Approved Drugs: Application to Drug Discovery

3. α-Hydroxyalkyl Heterocycles via Chiral Allylic Boronates: Pd-Catalyzed Borylation Leading to a Formal Enantioselective Isomerization of Allylic Ether and Amine

4. Optimization and multigram scalability of a catalytic enantioselective borylative migration for the synthesis of functionalized chiral piperidines

5. Concise Synthesis and Antimalarial Activity of All Four Mefloquine Stereoisomers Using a Highly Enantioselective Catalytic Borylative Alkene Isomerization

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2. Advances in Organoboron Chemistry;Reference Module in Chemistry, Molecular Sciences and Chemical Engineering;2023

3. Stereoselective synthesis through remote functionalization;Nature Synthesis;2022-01-12

4. Synthesis of saturated and partially saturated heterocyclic boronic derivatives;Tetrahedron;2022-01

5. A Diastereodivergent and Enantioselective Approach to syn- and anti-Diamines: Development of 2-Azatrienes for Cu-Catalyzed Reductive Couplings with Imines That Furnish Allylic Amines;Journal of the American Chemical Society;2021-08-23

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