Stereospecific, mechanism-based, suicide inhibition of a cytochrome P450 involved in ecdysteroid biosynthesis in the prothoracic glands of Manduca sexta

Author:

Warren James T.,Rybczynski Robert,Gilbert Lawrence I.

Publisher

Elsevier BV

Subject

Insect Science,Molecular Biology,Biochemistry

Reference71 articles.

1. The fate of the α-hydrogen of 5α-cholest-7-en-3β-ol in the conversion of 7-dehydrocholesterol by rat liver microsomes;Aberhart;J. Biol. Chem.,1971

2. Ecdysteroid biosynthesis by prothoracic glands of Pieris brassieae: Conversion in vitro of a radiolabelled precursor of 3-dehydroecdysone;Blais;C. R. Acad. Sci. Paris,1991

3. Phase separation of integral membrane proteins in Triton X-114 solution;Bordier;J. Biol. Chem.,1981

4. In vitro studies on potential selective and irreversible inhibitors of enzymes involved in the biosynthesis of ecdysone;Burger;Pesticide Biochem. Physiol.,1987

5. Aromatase: mechanism and inhibition;Cole,1992

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