Gas6/Axl-PI3K/Akt pathway plays a central role in the effect of statins on inorganic phosphate-induced calcification of vascular smooth muscle cells

Author:

Son Bo-Kyung,Kozaki Koichi,Iijima Katsuya,Eto Masato,Nakano Toru,Akishita Masahiro,Ouchi Yasuyoshi

Publisher

Elsevier BV

Subject

Pharmacology

Reference28 articles.

1. Statins inhibit reoxygenation-induced cardiomyocyte apoptosis: role for glycogen synthase kinase 3β and transcription factor β-catenin;Bergmann;J. Mol. Cell. Cardiol.,2004

2. Interleukin-3-induced phosphorylation of Bad through protein kinase Akt;del Peso;Science,1997

3. Relationship of calcified lesions to clinically significant atherosclerotic lesions;Eggen;Ann. N. Y. Acad. Sci.,1968

4. Medial artery calcification and its association with mortality and complications of diabetes;Everhart;Diabetologia,1988

5. Gas6 induces Axl-mediated chemotaxis of vascular smooth muscle cells;Fridell;J. Biol. Chem.,1998

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