Purinergic ionotropic P2X7 and metabotropic glutamate mGlu5 receptors crosstalk influences pro-inflammatory conditions in microglia

Author:

Chisari Mariangela,Barraco Michele,Bucolo Claudio,Ciranna Lucia,Sortino Maria Angela

Publisher

Elsevier BV

Subject

Pharmacology

Reference41 articles.

1. Shedding of microvesicles from microglia contributes to the effects induced by metabotropic glutamate receptor 5 activation on neuronal death;Beneventano;Front. Pharmacol.,2017

2. Enhanced Akt/GSK-3β/CREB signaling mediates the anti-inflammatory actions of mGluR5 positive allosteric modulators in microglia and following traumatic brain injury in male mice;Bhat;J. Neurochem.,2021

3. Recent advances in CNS P2X7 physiology and pharmacology: focus on neuropsychiatric disorders;Bhattacharya;Front. Pharmacol.,2018

4. The microglial ATP-gated ion channel P2X7 as a CNS drug target;Bhattacharya;Glia,2016

5. Microglia-produced nitric oxide and reactive nitrogen oxides mediate neuronal death;Boje;Brain Res.,1992

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