Presence of the methylenetetrahydrofolate reductase gene polymorphism MTHFR C677T in molar tissue but not maternal blood predicts failure of methotrexate treatment for low-risk gestational trophoblastic neoplasia
Author:
Funder
JSPS KAKENHI
Otsuka Toshimi Scholarship Foundation
Publisher
Elsevier BV
Subject
Pharmacology
Reference30 articles.
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2. The role of MTHFR and RFC1 polymorphisms on toxicity and outcome of adult patients with hematological malignancies treated with high-dose methotrexate followed by leucovorin rescue;Chiusolo;Cancer Chemother. Pharm.,2012
3. Genetic risk factors for drug-induced liver injury in rheumatoid arthritis patients using low-dose methotrexate;Davila-Fajardo;Pharmacogenomics,2013
4. FIGO staging for gestational trophoblastic neoplasia 2000. FIGO Oncology Committee;FIGO Oncology Committee;Int. J. Gynaecol. Obstet.,2002
5. A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase;Frosst;Nat. Genet.,1995
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1. Nucleoside transporter-guided cytarabine-conjugated liposomes for intracellular methotrexate delivery and cooperative choriocarcinoma therapy;Journal of Nanobiotechnology;2021-06-15
2. Common Methylenetetrahydrofolate Reductase Polymorphisms (A1298C & C677T) in Ectopic Trophoblasts and Methotrexate Treatment Failure in Tubal Pregnancies;Ginekologia Polska;2018-10-31
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