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SGLT2 inhibitors and metformin: Dual antihyperglycemic therapy and the risk of metabolic acidosis in type 2 diabetes

  • Published:2019-03 Issue: Volume:846 Page:23-29
  • ISSN:0014-2999
  • Container-title:European Journal of Pharmacology
  • language:en
  • Short-container-title:European Journal of Pharmacology

Author:

Donnan Katherine,Segar Lakshman

Funder

National Heart, Lung, and Blood Institute

National Institutes of Health

University of Georgia Research Foundation

University of Georgia RC Wilson Pharmacy Fund

Publisher

Elsevier BV

Subject

Pharmacology

Reference56 articles.

1. Standards of medical care in diabetes;American Diabetes Association;Diabetes Care,2017

2. Long-term metformin use and vitamin b12 deficiency in the diabetes prevention program outcomes study;Aroda;J. Clin. Endocrinol. Metab.,2016

3. Metformin;Bailey;N. Engl. J. Med.,1996

4. Inhibition of the glucose transporter SGLT2 with dapagliflozin in pancreatic alpha cells triggers glucagon secretion;Bonner;Nat. Med.,2015

5. Lactic acidosis: relationship between metformin levels, lactate concentration and mortality;Boucaud-Maitre;Diabet. Med.,2016

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