Coronaridine congeners induce sedative and anxiolytic-like activity in naïve and stressed/anxious mice by allosteric mechanisms involving increased GABAA receptor affinity for GABA-Reference-Cited by-同舟云学术

Coronaridine congeners induce sedative and anxiolytic-like activity in naïve and stressed/anxious mice by allosteric mechanisms involving increased GABAA receptor affinity for GABA

Published:2023-08 Issue: Volume:953 Page:175854
ISSN:0014-2999
Container-title:European Journal of Pharmacology
language:en
Short-container-title:European Journal of Pharmacology

Author:

Arias Hugo R.,De Deurwaerdère Philippe,Scholze Petra,Sakamoto Seiji,Hamachi Itaru,Di Giovanni Giuseppe,Chagraoui Abdeslam^ORCID

Funder

Center for Health Sciences, Oklahoma State University

Office of the Vice President for Research, University of Minnesota

Vienna Science and Technology Fund

Publisher

Elsevier BV

Subject

Pharmacology

Reference34 articles.

1. A possible mechanism for anxiolytic and antidepressant effects of alpha- and beta-amyrin from Protium heptaphyllum (Aubl.) March;Aragão;Pharmacol. Biochem. Behav.,2006

2. (+)-Catharanthine potentiates the GABA(A) receptor by binding to a transmembrane site at the β(+)/α(-) interface near the TM2-TM3 loop;Arias;Biochem. Pharmacol.,2022

3. (+)-Catharanthine and (-)-18-methoxycoronaridine induce antidepressant-like activity in mice by differently recruiting serotonergic and norepinephrinergic neurotransmission;Arias;Eur. J. Pharmacol.,2023

4. (+)-Catharanthine and (-)-18-methoxycoronaridine induce antidepressant-like activity in mice by differently recruiting serotonergic and norepinephrinergic neurotransmission;Arias;Eur. J. Pharmacol.,2023

5. Coronaridine congeners potentiate GABA(A) receptors and induce sedative activity in mice in a benzodiazepine-insensitive manner;Arias;Prog. Neuro-Psychopharmacol. Biol. Psychiatry,2020

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