The novel, peripherally restricted GABAB receptor agonist lesogaberan (AZD3355) inhibits acid reflux and reduces esophageal acid exposure as measured with 24-h pHmetry in dogs
Author:
Publisher
Elsevier BV
Subject
Pharmacology
Reference23 articles.
1. Synthesis and pharmacological evaluation of novel gamma-aminobutyric acid type B (GABAB) receptor agonists as gastroesophageal reflux inhibitors;Alstermark;J. Med. Chem.,2008
2. Does the presence of a hiatal hernia affects the efficacy of the reflux inhibitor baclofen during add-on therapy?;Beaumont;Am. J. Gastroenterol.,2009
3. Effect of acute and chronic administration of the GABAB agonist baclofen on 24 hour pH metry and symptoms in control subjects and in patients with gastro-oesophageal reflux disease;Ciccaglione;Gut,2003
4. Pathogenesis of gastro-oesophageal reflux disease and novel options for its therapy;Dent;Neurogastroenterol. Motil.,2008
5. Proton-pump inhibitor therapy in patients with gastro-oesophageal reflux disease: putative mechanisms of failure;Fass;Drugs,2007
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2. A double-blind randomised placebo-controlled trial investigating the effects of lesogaberan on the objective cough frequency and capsaicin-evoked coughs in patients with refractory chronic cough;ERJ Open Research;2022-01
3. Repositioning of a novel GABA-B receptor agonist, AZD3355 (Lesogaberan), for the treatment of non-alcoholic steatohepatitis;Scientific Reports;2021-10-21
4. Synopsis of recent synthetic methods and biological applications of phosphinic acid derivatives;Tetrahedron;2020-06
5. KFP-H008 blocks gastric acid secretion through inhibiting H+-K+-ATPase;European Journal of Pharmacology;2017-09
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