KFP-H008 blocks gastric acid secretion through inhibiting H+-K+-ATPase
Author:
Funder
Qinglan Project
National Major Scientific and Technological Special Project
Publisher
Elsevier BV
Subject
Pharmacology
Reference47 articles.
1. Conformational rearrangement of gastric H(+),K(+)-ATPase induced by an acid suppressant;Abe;Nat. Commun.,2011
2. Application of a combined effect compartment and binding model for gastric acid inhibition of AR-HO47108: a potassium competitive acid blocker, and its active metabolite AR-HO47116 in the dog;Äbelö;Eur. J. Pharm. Sci.,2006
3. Vonoprazan-based therapy for Helicobacter pylori eradication: experience and clinical evidence;Akazawa;Ther. Adv. Gastroenterol.,2016
4. Discovery of a novel pyrrole derivative 1-[5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)–1H-pyrrol-3-yl]-N-methylmethanamin e fumarate (TAK-438) as a potassium-competitive acid blocker (P-CAB);Arikawa;J. Med. Chem.,2012
5. Inhibiting the proton pump: mechanisms, benefits, harms, and questions;Aronson;BMC Med.,2016
Cited by 14 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Potassium-competitive Acid Blockers: Current Clinical Use and Future Developments;Current Gastroenterology Reports;2024-08-15
2. Tegoprazan as a New Remedy for Gastrointestinal Diseases in Comparison with its Therapeutic Predecessors: A Mini-Review;Current Drug Research Reviews;2024-03
3. Predicting pharmacodynamic effects through early drug discovery with artificial intelligence-physiologically based pharmacokinetic (AI-PBPK) modelling;Frontiers in Pharmacology;2024-02-16
4. Keverprazan, a novel potassium-competitive acid blocker: Single ascending dose safety, tolerability, pharmacokinetics, pharmacodynamics and food effect in healthy subjects;European Journal of Pharmaceutical Sciences;2023-11
5. Keverprazan, a novel potassium‐competitive acid blocker: Multiple oral doses safety, tolerability, pharmacokinetics, and pharmacodynamics in healthy subjects;Clinical and Translational Science;2023-08-02
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3