A novel role of the antitumor agent tricyclodecan-9-yl-xanthogenate as an open channel blocker of KCNQ1/KCNE1

Author:

Wu Meikui,Takemoto Makoto,Luo Huan,Xu Jian-Jun,Lu Mei-Hong,Kameyama Masaki,Takumi Toru,Song Wen-Jie

Publisher

Elsevier BV

Subject

Pharmacology

Reference39 articles.

1. Biology of the KCNQ1 potassium channel;Abbott;New J. Sci.,2014

2. Tricyclodecan-9-yl- Xanthogenate (D609) mechanism of actions: A mini-review of literature;Adibhatla;Neurochem Res,2012

3. Exchange protein directly activated by cAMP mediates slow delayed-rectifier current remodeling by sustained β-adrenergic activation in guinea pig hearts;Aflaki;Circ. Res.,2014

4. Muscarinic modulation of a transient K+ conductance in rat neostriatal neurons;Akins;Nature,1990

5. The antiviral, antitumoural xanthate D609 is a competitive inhibitor of phosphatidylcholine-specific phospholipase C;Amtmann;Drugs Exp. Clin. Res.,1996

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