Guiding lead optimization with GPCR structure modeling and molecular dynamics
Author:
Publisher
Elsevier BV
Subject
Drug Discovery,Pharmacology
Reference49 articles.
1. Structures of G protein-coupled receptors reveal new opportunities for drug discovery;Cooke;Drug Discov Today,2015
2. The druggable genome: evaluation of drug targets in clinical trials suggests major shifts in molecular class and indication;Rask-Andersen;Annu Rev Pharmacol Toxicol,2014
3. Target validation of G-protein coupled receptors;Wise;Drug Discov Today,2002
4. How many drug targets are there?;Overington;Nat Rev Drug Discov,2006
5. GPCR structure, function, drug discovery and crystallography: report from Academia-Industry International Conference (UK Royal Society) Chicheley Hall, 1–2 September 2014;Heifetz;Naunyn Schmiedebergs Arch Pharmacol,2015
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