The Predicted Structure of the Headpiece of the Huntingtin Protein and Its Implications on Huntingtin Aggregation

Author:

Kelley Nicholas W.,Huang Xuhui,Tam Stephen,Spiess Christoph,Frydman Judith,Pande Vijay S.

Publisher

Elsevier BV

Subject

Molecular Biology,Structural Biology

Reference32 articles.

1. A polymorphic DNA marker genetically linked to Huntington's disease;Gusella;Nature,1983

2. A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. The Huntington's Disease Collaborative Research Group;Mac Donald;Cell,1993

3. Phenotypic characterization of individuals with 30–40 CAG repeats in the Huntington disease (HD) gene reveals HD cases with 36 repeats and apparently normal elderly individuals with 36–39 repeats;Rubinsztein;Am. J. Hum. Genet.,1996

4. Identification of an HD patient with a (CAG)180 repeat expansion and the propagation of highly expanded CAG repeats in lambda phage;Sathasivam;Hum. Genet.,1997

5. Solution structure of polyglutamine tracts in GST–polyglutamine fusion proteins;Masino;FEBS Lett.,2002

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